I have a question regarding the Shapework application. If I have already applied N shapes to build a shape statistical model (SSM) with Shapeworks and have created a clinical predictive model based on the PCA component scores. Now, I want to test the accuracy of clinical predictive model in new cases. Therefore, i need to calculate the PCA component scores based on the shape statistical model built before in the new cases. How should I do it? Can Shapeworks calculate PCA component scores with new cases without rebuilt a new SSM? Thank you!
Yes, this can be accomplished by using the “fixed_domans” feature. An example is provided here:
Essentially, you do re-run the optimization, but your original shapes are held constant (fixed), allowing the new shapes to conform to the existing shape model.